Ultrastructural demonstration of rat myofibroblasts in phenytoin-induced gingival overgrowth.
نویسندگان
چکیده
منابع مشابه
Phenytoin-induced gingival overgrowth.
Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin-induced gingival overgrowth (PIGO), which is a time-dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth ...
متن کاملAmlodipine-induced gingival overgrowth.
Amlodipine is a calcium channel blocker used in the management of angina and hypertension. We report 3 cases of gingival overgrowth in adult dentate patients associated with chronic usage of this drug. Gingival changes occurred within 3 months of dosage and appeared to be compounded by the patient's existing periodontal condition. In all 3 patients, there was sequestration of amlodipine in thei...
متن کاملDrug-induced Gingival Overgrowth
Many terms have been used to describe gingival overgrowth. The expression gingival hyperplasia (“abnormal increase in the number of normal cells in a normal arrangement in an organ or tissue, which increase in volume”) and gingival hypertrophy (“enlargement or overgrowth of an organ or part due to an increase in size of its constituent cells”) have been also used, although gingival overgrowth i...
متن کاملPhenytoin-induced gingival enlargement.
To cite: Chacko LN, Abraham S. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014204670 DESCRIPTION Gingival overgrowth occurs as a side effect of some systemic medications. It is now well established that phenytoin is one such agent. It has multiple therapeutic indications ranging from convulsive disorders and neuralgias to cardiac arrhythmia. The incidence rat...
متن کاملLack of Mutations in PIK3CA, p14ARF, p16INK4a and p21Waf1/Cip1 in Phenytoin-Induced Gingival Overgrowth
Seizure episodes associated with generalized tonic clonic or partial seizure disorder is a life style debilitating disease. Several drugs have been developed, which are in use to control seizure episodes include carbamazepine, ethosuximide, felbamate, lamotrigine and phenytoin (Das et al., 2012; Bialer et al., 2013). While a long list of drug exists, phenytoin is preferred drug of choice as it:...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Oral Biology
سال: 1993
ISSN: 0385-0137
DOI: 10.2330/joralbiosci1965.35.496